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Welcome to The Pittsburgh Newsletter!

In today’s edition:

• Professional Bull Riders tour to host first ever Pittsburgh event at PPG Paints Arena.

• Upcoming David Nail concert

• A deep-dive into the life of Jeff Goldblum

• And more…

Quote of the Week

“The world is changed by your example, not by your opinion.”

–Paulo Coelho

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Trivia

Here is your trivia question of the week. The answer will be shown in next week’s newsletter. Which do you think it is? No cheating!

The first commercial radio station in the U.S., KDKA, began broadcasting in Pittsburgh in what year?

A) 1910

B) 1920

C) 1930

D) 1945

Answer to Last Week's Trivia: Primanti Bros. sandwich shop in Pittsburgh was established in B) 1933.

News

💼Business

USGA CEO Mike Whan talks about bringing U.S. Open to Oakmont Country Club. (Link)

Clayton Kendall acquires Polish Hill printing firm in all-Pittsburgh transaction. (Link)

🏒Sports

MLB Trade Grades: Isiah Kiner-Falefa, having a career year, fills a need for the Pirates. (Link)

NFL stadium guides: Share your best beer, food and tailgating options for all 32 teams. (Link)

🏦Finance

Professional Bull Riders tour to host first ever Pittsburgh event at PPG Paints Arena. (Link)

Upcoming Events

Here are some events that are happening in our city this week. There is a good mix between sports, entertainment, conferences, concerts, and more.

Sports

⚾ Arizona Diamondbacks at Pittsburgh Pirates
PNC Park, Pittsburgh
Friday, August 2 to Sunday, August 4, 2024 | (More info)

⚾ San Diego Padres at Pittsburgh Pirates
PNC Park, Pittsburgh
Wednesday, August 7 to Thursday, August 8, 2024 | (More info)

Music & Concerts

🎵 Debbie Gibson
Stage AE, Pittsburgh
Friday, August 2, 2024 | (More info)

🎵 David Nail
Highmark Stadium, Pittsburgh
Saturday, August 3, 2024 | (More info)

Family

🎨 Kids Summer Art Series with Atithi Studios
1020 North Canal Street, Pittsburgh
Monday, August 5, 2024 | (More info)

Image of the Week

Every week, I have a habit of making some AI art about our city.

This week, I typed in “Pittsburgh with a transportation system based on personal drones” and this is what I got.

Let me know what ideas you have for this. I really enjoy making these types of photos.

Pittsburgh Historical Events

1985: The discovery of the Pittsburgh compound B, significant in Alzheimer’s research.

In 1985, a significant discovery was made in Alzheimer's research with the identification of the Pittsburgh compound B (PiB). This compound, developed by researchers at the University of Pittsburgh, plays a crucial role in visualizing Alzheimer's in the living brain. PiB attaches to deposits of beta-amyloid, the toxic protein that accumulates in the brains of individuals with Alzheimer's. Prior to this discovery, the diagnosis of Alzheimer's disease could only be confirmed through postmortem examination of the brain. The development of PiB has opened up new possibilities for early detection and research in the field of Alzheimer's disease.

The use of Pittsburgh compound B has revolutionized the study of Alzheimer's disease, particularly in the realm of brain imaging and diagnostic testing. PiB is a radioactive analog of thioflavin T, and it can be utilized in positron emission tomography (PET) scans to visualize beta-amyloid plaques in neuronal tissue. This breakthrough has paved the way for investigational studies and clinical trials aimed at understanding the progression of Alzheimer's disease and developing potential treatments. The advent of PiB has provided researchers with a powerful tool to detect the early stages of cerebral amyloidosis, a major pathological component of Alzheimer's disease, in living humans using PET technology.

The impact of Pittsburgh compound B extends beyond its role in visualizing Alzheimer's in the living brain. It has also contributed to the development of imaging-based biomarkers for Alzheimer's disease. Postmortem PiB binding has shown promise in distinguishing Alzheimer's disease from control cases, and further research is underway to explore the potential of PiB as a diagnostic tool. The continued development of in vivo imaging agents, such as Pittsburgh compound B, holds promise for advancing our understanding of Alzheimer's disease and improving diagnostic capabilities.

Famous People From Pittsburgh

Jeff Goldblum (1952–present): Actor and musician.

Jeff Goldblum, a renowned actor and musician, has captivated audiences with his unique charm and versatile performances. From his early days in Pittsburgh to his global stardom, Goldblum's journey is a testament to his passion for the arts and his enduring impact on the entertainment industry.

Early Life and Pittsburgh Roots

Jeffrey Lynn Goldblum was born to Jewish parents in West Homestead, Pennsylvania, located just outside of Pittsburgh. His formative years in Pittsburgh laid the foundation for his future career in the entertainment industry. Goldblum has fondly reminisced about his youth in the Pittsburgh area, emphasizing the happy times he spent growing up in West Homestead.

Rise to Stardom in Acting and Music

Goldblum's career in acting and music has been marked by a series of iconic roles and memorable performances. His on-screen presence in films such as Jurassic Park, The Fly, and Independence Day has solidified his status as a Hollywood legend. Additionally, Goldblum's musical talents have been showcased through his jazz band, which released its first album, The Capitol Studios Sessions, in 2018.

Versatility and Influence

Goldblum's versatility as an actor and musician has earned him a dedicated fan base and critical acclaim. His ability to seamlessly transition between dramatic roles and comedic performances has set him apart in the entertainment industry. Furthermore, Goldblum's influence extends beyond his artistic endeavors, as he continues to use his platform to raise awareness and support important social and environmental causes.

Continued Connection to Pittsburgh

Despite achieving global stardom, Goldblum has maintained a strong connection to Pittsburgh, expressing his fondness for the city and his eagerness to return for future visits. His ties to Pittsburgh serve as a reminder of his humble beginnings and the impact of his upbringing on his career and personal life.

Key Achievements of Jeff Goldblum:

• Iconic roles in blockbuster films such as Jurassic Park, The Fly, and Independence Day.

• Successful music career with the release of his jazz band's album, The Capitol Studios Sessions.

• Versatile performances showcasing his range as an actor and musician.

• Advocacy for important social and environmental causes, using his influence for positive change.

• Fondly remembering his Pittsburgh roots and expressing a desire to return to the city.

In summary, Jeff Goldblum's journey from his Pittsburgh roots to global stardom is a testament to his enduring impact on the entertainment industry. His versatile talents, influential presence, and continued connection to Pittsburgh reflect a remarkable career shaped by passion, dedication, and a genuine love for the arts.

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-Matthew Larsen

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